This event examines concerns related to the mental health impacts and clinical evidence surrounding pediatric gender-affirming medical interventions. It highlights ongoing policy debates, emerging international regulatory approaches, and the importance of prioritizing mental health support for children and adolescents experiencing gender distress. The discussion aims to inform policymakers, professionals, and families about safety considerations, alternative therapeutic approaches, and the need for evidence-based, child-centred care that supports well-being and informed decision-making.